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Product Description This book is designed to explain to dental students the processes of diagnosis and treatment planning, through consideration of clinical cases and problems associated with aspects of all dental specialties. It presents a series of case histories from all the major areas of dentistry, and uses a question-and-answer format to guide readers through the process of examination, differential diagnosis, investigations, diagnosis and treatment. It prepares readers for the wide variety of problems likely to be encountered in clinical practice. Download buku di. Product Description This is a third edition of the dominant textbook in this field, which is used in nearly all dental schools in the UK and in many other countries. Covers both radiography (producing the image) and radiology (interpreting the image) and presents the subject in an accessible format.
This new edition has been revised in accordance with important new guidelines on radiation protection which came into force in January 2000. Download buku di semoga bermanfaat yah ^_^ Essentials Of Traumatic Injuries To The Teeth Andreasen. Product Description This is a readily accessible, fully illustrated guide to the initial treatment of acute dental injuries. The clinician is guided through the initial examination of the traumatized patient to the design of a rational, individualised treatment plan. This approach is aimed at minimizing the risk of long-term complications and, thereby, alleviating the uncertainty of the future of the the traumatized dentition both for the patient, dentist and for other concerned individuals. The material is drawn from clinical investigations, statistical analysis of 20,000 records of patients treated for acute dental injuries over 25 years, and results from 100 experimental studies. Download buku di semoga bermanfaat yah ^_^.
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Changes in our lifestyle have resulted in a worldwide increased prevalence of obesity-related metabolic diseases such as type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Besides excessive caloric intake, a high-fructose consumption has been implicated in the accelerated development of metabolic diseases. The small intestine is the major site for fructose uptake and metabolism, while excessive fructose intake is known to cause metabolic adverse effects in the liver.
In the first part of the thesis we studied the transcriptional effects of a fructose diet in the small intestine (duodenum) and liver. Fructose as compared to glucose intake has distinct effects on the small intestinal and liver transcriptomes in mice, and these effects were more profound in the small intestine. Systemic activation of nuclear receptors (NRs) has been successfully applied in the pharmaceutical industry to treat various diseases. This strategy, however, often causes major adverse effects due to the pleiotropic target genes of NRs.
Intestinal nutrient uptake and metabolism are important for whole-body energy homeostasis; therefore, we explored the potential of intestinal NR activation in the regulation of whole-body energy homeostasis. We identified several facilitative glucose transporters (GLUT-members) as novel NR target genes. In addition, we identified the NR PPARdelta as an intestinal regulator of whole-body metabolism by protecting against diet-induced obesity and increasing high-density lipoprotein (HDL) HDL-cholesterol levels. Taken together, selective pharmacologic modulators of NRs that act solely in the gastrointestinal tract are an effective way of inducing beneficial effects on whole-body metabolism while minimising systemic adverse effects.